椎体增强技术在恶性肿瘤椎体压缩性骨折中的应用进展

Progress of vertebral augmentation technology' s application in malignant tumor vertebral compression fracture

与骨质疏松椎体压缩性骨折(VCF)相比,恶性肿瘤VCF的保守治疗效果不佳。椎体成形术和球囊扩张后凸成形术的优势在于即刻减轻病椎疼痛、保证化学治疗或放射治疗按时进行、便于护理、易于活体组织检查、恢复椎体高度和骨水泥潜在的抗肿瘤效应。随机试验结果显示对有VCF的恶性肿瘤患者而言,椎体增强技术治疗效果确切,同时,椎体增强技术可以结合术中活体组织检查、射频消融、辅助性放射治疗等。

Compared with the effect of osteoporotic vertebral compression fractures（ VCF）,the outcome of conservative treatment for VCF of malignant tumor is presumably different. Advantages of vertebral body enhancements include immediate pain relief,avoiding delays in chemoradiation,outpatient care in the majority of cases,biopsy,vertebral height restoration,and potential antitumor effect of bone cement. Vertebral body enhancements have been shown by randomized studies to be effective in treating malignant tumor patients with VCF. In addition,they can be combined with intraoperative biopsy or radiofrequency ablation and adjuvant or neoadjuvant radiation treatment.