急性心肌梗死患者短期心脏康复治疗对超敏C-反应蛋白的影响

The Impact of hsC RP in AMI Patients after Short-Term Cardiac Recovery Treatment

目的:探讨急性心肌梗死后2周的心脏康复治疗对超敏C-反应蛋白及其他危险因素的影响,以评估其疗效。方法:测定30例急性心梗后男性患者2周心脏康复治疗前后的超敏C-反应蛋白值及其他危险因素。对照组为30例年龄相当的健康男性,无已知的冠心病危险因素。结果:与健康对照组相比,观察组超敏C-反应蛋白值更高,心脏康复治疗后,超敏C-反应蛋白及代谢综合征相关参数显著降低(P<0.05),但仅表现于非吸烟者及不伴焦虑或抑郁者。结论:2周的心脏康复治疗可显著降低超敏C-反应蛋白及代谢综合征参数。然而这一效应仅显著表现于非吸烟者及不伴情感障碍者。因此急性心肌梗死治疗期间所有患者应戒烟,伴情感障碍者应同时给予精神类药物。

Objective： To investigate the impact of hsCRP and other risk factors in patients with acute myocardial infarction（ AMI） after 2- week cardiac recovery treatment. Methods： The hsCRP and other risk factors were measured before and after 2- week recovery treatment in 30 men with AMI. The comparison group was made of 30 similar age healthy men with no risk factors of coronary heart disease. Results： The patients with AMI had higher values of hs CRP than healthy men. Furthermore,smokers and patients with anxiety or depression had much higher values of hs CRP. After recovery treatment,there was a remarkable drop in values of hs CRP and metabolic syndrome parameters（ P 0. 05） in nonsmokers,and in patients without anxiety or depression. Conclusion： The hs CRP and metabolic syndrome parameters can be remarkable reduced after 2-week cardiac recovery treatment. However,this effect is present only in nonsmokers and patients without emotion disorder. Thus,all AMI patients should be advised to quit smoking,those patients with emotion disorder should be given psychotropic drugs during treatment.