101例甲状腺结节的临床及病理分析

Analysis of the Clinical Data of Ultrasound-Guided Fine-Needle Aspiration Biopsy in the Patients with Thyroid Nodules

目的：探讨甲状腺结节患者临床特点及超声引导下细针穿刺活检病理结果分析,评估无创及微创检查对甲状腺结节良恶性鉴别的临床意义。方法：分析2009年1月至2013年7月在成都军区总医院内分泌科住院的101例甲状腺结节患者的临床资料。结果：甲状腺结节高发年龄为41~50岁,男女发病比例为1∶5.3,甲状腺功能异常者占总数的54.45%,甲状腺超声检查发现单发结节占46.53%,多发结节占53.47%;63例行超声引导下细针穿刺活检,其中良性病变占总数的87.30%;不确定及可疑恶性病变占总数的9.52%。结论：甲状腺结节在几乎所有年龄段均有发病,甲状腺结节患者甲状腺功能异常约占一半,甲状腺超声在诊断中常被列为首选检查,超声引导下细针穿刺活检更是对良恶性鉴别有重要价值,有助于甲状腺结节术前评估。

Objective： To investigate the clinical characteristic and the pathological results of ultrasound- guided fine- needle aspiration biopsy（ US- FNAB） in patients who were discovered thyroid nodules; and to assess the clinical importance of noninvasive or minimal invasive diagnostic methods for thyroid nodules.Methods： Analysed the clinical data of 101 patients with thyroid nodules from January 2009 to July 2013 in Department of Endocrinology,Chengdu General Military Hospital. Results： The most high- risk of thyroid nodule resided in the group aged 41 ~ 50,It was ratio 1： 5. 3 F： M. The rate of abnormal thyroid function was54. 45%,the rate of solitary nodule was 46. 53%,and the multiple nodules was 53. 47% by ultrasonography. 63 patients who suffered from thyroid nodules had US- FNAB. the rate of benign nodules was87. 3%,the suspicious malignant ones was 9. 52%. Conclusion： Thyroid nodules almost happen in all age groups,the half of all patients have abnormal thyroid function; ultrasonography of thyroid is the first choice in the diagnosis,US- FNAB has great value in distinguishing benign nodules and malignant ones,and more help with preoperative assertion.