大便隐血与大肠疾病关系的研究

Research of the relationship between fecal occult blood and colorectal disease

目的研究大便隐血与大肠疾病的关系,说明大便隐血检测在大肠疾病诊断中的作用。方法收集2012年3月～2014年3月份在上海市松江区九亭医院内镜室行肠镜检查患者粪便隐血实验结果 ,并与肠镜检查结果结合分析粪便隐血与大肠疾病的关系。结果大便隐血在大肠癌、异型增生、炎症性肠病、腺瘤、非腺瘤息肉、肠道炎症及无异常中的阳性率分别为83.33%、83.33%、66.67%、61.67%、39.22%、33.33%、6.16%。大肠癌大便隐血阳性率分别高于非腺瘤息肉、肠道炎症、正常肠黏膜（P〈0.05）。癌前病变（异型增生、腺瘤）大便隐血阳性率分别高于非腺瘤息肉、肠道炎症、正常肠黏膜（P〈0.05）。结论粪便隐血与大肠癌及癌前病变有重要的关系,因此大便隐血实验对于大肠癌及癌前病变的早期筛查有重要意义。

Objective To study the relationship between fecal occult blood and colorectal disease to indicate the role of fecal occult blood test in the diagnosis of colorectal diseases. Methods The fecal occult blood testing results of the patients checked by colonoscopy in endoscopy room at Jiuting hospital of Songjiang District in Shanghai city from March2012 to March 2014 were collected,and the relationship between fecal occult blood and colorectal disease was analyzed combined with the results of the colonoscopy. Results The positive rate of occult blood test in colorectal cancer, ysplasia,inflammatory bowel disease,adenoma,non-adenomatous polyp,intestinal inflammatory and no abnormality was83.33%,83.33%,66.67%,61.67%,39.22%,33.33%,6.16% respectively.The positive rate of occult blood in colorectal cancer was respectively higher than non-adenomatous polyp,intestinal inflammatory,normal intestinal mucosa（P〈0.05）.The positive rate of occult blood in precancerous lesion（adenoma,dysplasia） was respectively higher than non-adenomatous polyp,intestinal inflammatory,normal intestinal mucosa（P〈0.05）. Conclusion Fecal occult blood has more important relationship with colorectal cancer and precancerous lesion,so it is very nessesary for fecal occult blood test for screening colorectal cancer and precancerous lesion early.