期刊文献+

磁共振弥散加权成像在三阴性乳腺癌新辅助化疗中疗效评价中的价值 被引量:4

下载PDF
导出
摘要 乳腺癌新辅助化疗(neoadjuvant chemotherapy,NAC)的意义是使局部晚期的乳腺癌患者达到手术机会以及不能保乳的患者拥有保乳机会。乳腺癌病理分型分小叶癌及导管癌,导管癌发生在乳腺腺叶导管腺上皮,并可以沿导管播散的特点,所以传统的影像学方法因不能准确地显示化疗后是否有肿瘤残存以及残存病灶的范围导致在术前不能准确地制定手术计划。Garimella等[1]第186例乳腺癌新辅助化疗后进行外科手术的患者进行随访研究得出结论:对于乳腺癌新辅助化疗后的患者,依据术前磁共振成像(MRI)检查进行保乳手术方案的,可以减少术后复发率。 Nagashima等[2]认为肿瘤的体积缩减率是预测新辅助化疗后未取得病理完全缓解(pathologic complete response,PCR)患者术后早期预后的重要因素,而磁共振(MR)不仅能最准确地评价新辅助化疗前后病灶体积变化,而且通过扩散加权成像(diffusion-weight-ed imaging,DWI)等功能成像技术对乳腺癌新辅助化疗疗效进行早期评价和疗效预测。本文旨在研究MR DWI在三阴性乳腺癌新辅助化疗疗效评价中的价值。
出处 《中国药物与临床》 CAS 2014年第12期1652-1653,共2页 Chinese Remedies & Clinics
  • 相关文献

参考文献7

  • 1Garimella V,Qutob O,Fox JN,et al.Recurrence rates after DCEMRI image guided planning for breat-conserving surgery following neoadjuvant chemotherapy for locally advanced breast cancer patients[J].Eur J Surg Oncol,2007,33(2):157-161.
  • 2Nagshima T,Sakakibara M,Sangai T,et al.Tumor reduction rte predicts early recurrence in patients with breast cancer failing to achieve complete response to primary chemotherapy[J].Breast Cancer,2010,17(2):125-130.
  • 3Pickles MD,Gibbs P,Lowry M,et al.Diffusion changes precede size reduction in neoadjuvant treatment of breast cancer[J].Magn Reson Imaging,2006,24(7):843-847.
  • 4Hylton N.MR imaging for assessment of breast cancer response to neoadjuvant chemotherapy[J].Magn Reson Imaging Clin N Am,2006,14(3):383-389.
  • 5汪晓红,李瑞敏,彭卫军.磁共振功能成像在乳腺癌新辅助化疗早期疗效评价中的应用[J].磁共振成像,2011,2(3):172-176. 被引量:20
  • 6Warren LM,Given-Wilson RM,Wallis MG,et al.The effect of image processing on the detection of cancers in digital mammography[J].Am J Roentgenol,2014,203(2):387-393.
  • 7Sharma P,Stecklein SR,Kimler BF,et al.The prognostic value of BRCAI promoter mehtylation in early stage triple negative breast cancer[J].Cancer Ther Res,2014,3(2):1-11.

二级参考文献34

  • 1Tofts PS,Brix G,Buckley DL,et al.Estimating kinetic parameters from dynamic contrast-enhanced T1-weighted MRI of a diffusable tracer:standardized quantities and symbols.J Magn Reson Imaging,1999,10(3):223-232.
  • 2Semple SI,Harry VN,Parkin DE,et al.A combined pharmacokinetic and radiologic assessment of dynamic contrast-enhancement magnetic resonance imaging predicts response to chemoradiation in locally advanced cervical cancer.Int Radiat Oncol Biol Phys,2009,75(2):611-617.
  • 3Tofts PS.Modeling tracer kinetics in dynamic Gd-DTPA MR imaging.J Magn Reson Imaging,1997,7(1):91-101.
  • 4Huang W,Li X,Morris EA,et al.The magnetic resonance shutter speed discriminates vascular properties of malignant and benign breast tumors in vivo.Proc Natl Acad Sci USA,2008,105(46):17943-17948.
  • 5Charfare H,Limongelli S,Purushotham AD,et al.Neoadjuvant chemotherapy in breast cancer.Br J Surg,2005,92(1):14-23.
  • 6Partridge SC,Gibbs JE,Lu Y,et al.MRI measurements of breast tumor volume predict response to neoadjuvant chemotherapy and recurrence-free survival.AJR Am J Roentgenol,2005,184(6):1774-1781.
  • 7Roben SM,Leach MO.Imaging biochemistry:applications to breast cancer.Breast Cancer Res,2001,3(1):36-40.
  • 8Hylton N.MR imaging for assessment of breast cancer response to neoadjuvant chemotherapy.Magn Reson Imaging Clin N Am,2006,14(3):383-389.
  • 9Junkermann H,Fournier D von.Imaging procedures for assessment of the response of mammary carcinoma to preoperative chemotherapy.Radiology,1997,37(9):726-732.
  • 10Pickles MD,Gibbs P,Lowry M,et al.Diffusion changes precede size reduction in neoadjuvant treatment of breast cancer.Magn Reson Imaging,2006,24(7):843-847.

共引文献19

同被引文献63

  • 1张静,程流泉,安宁豫,等.磁共振扩散加权成像在乳腺肿块和非肿块性病变中应用价值的对比研究[J].功能与分子医学影像学.2012,1(2):39-43.
  • 2柯于海,孙美,周锋江,等.核磁共振在乳腺癌诊断中的价值[J].医药前沿,2011,1(23):191-192.
  • 3de Ronde J J, Hannemann J, Halfwerk H,et al. Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response[J]. Breast Cancer Res Treat, 2010,119(1) :119-126.
  • 4Balmanoukian A, Zhang Z,Jeter S, et al. African American women who receive primary anthracycline-and taxane-based chemotherapy for triple-negative breast cancer suffer worse outcomes compared with white women[J]. J Clin Oncol,2009,27(22):e35-37.
  • 5Youk J H, Son E J, Chung J, et al. Triple-negative invasive breast cancer on dynamic contrast-enhanced and diffusion-weighted MR imaging:comparison with other breast cancer subtypes[J]. Eur Radiol,2012,22(8) : 1724-1734.
  • 6Chen J H, Agrawal G, Feig B, et al. triple negative breast cancer: MRI features in 29 patients[J]. Ann Oncol,2007,18(12) : 2042- 2043.
  • 7Uematsu T, Kasami M, Yuen S. Triplenegative breast cancer: correlation between MR imaging and pathological findings [J]. Radiology, 2009,250(3) :638-647.
  • 8Dogan B E, Gonzalez-Angulo A M, Gilcrease M, et al. Multimodality imaging of triple receptor-negative tumors with mammography, ultra- sound, and MRI[J]. Am J Roentgenol, 2010,194(4) : 1160- 1166.
  • 9Jeh S K, Kim S H, Kim H S, et al. Correlation of the apparent diffusion coefficient value and dynamic magnetic resonance ima-ging find- ings with prognostic factors in invasive ductal earcinoma[J]. J Magn Reson Imaging, 2011,33 (1) : 102 - 109.
  • 10朱凤婷,钟锦双,许桂晓,等.比较DWI与动态增强扫描在诊断乳腺良恶性病变中的差异[J].中华临床医师杂志,2013,7(9):4117-4119.

引证文献4

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部