超声光散射成像技术在乳腺癌诊断中的应用价值

Diagnostic value of combining Doppler ultrasound and diffuse optical tomography in breast cancer

目的:应用超声光散射成像技术及彩色多普勒超声,探讨其在乳腺癌诊断中的临床应用价值。方法:选取我院乳腺外科行外科手术治疗的女性患者103例,共156个乳腺包块,术前超声常规检查乳腺包块。彩色多普勒超声探查血流分级情况,同时超声光散射系统测量总血红蛋白浓度。每种方法分别计算准确度、敏感度、特异度、阳性预测值和阴性预测值,对乳腺肿物诊断的准确度进行组间分析。结果:超声光散射成像技术诊断乳腺癌的准确度、敏感度、特异度、阳性预测值和阴性预测值分别为76.9%、89.6%、67.4%、67.4%、89.6%。彩色多普勒超声诊断乳腺癌的准确度、敏感度、特异度、阳性预测值和阴性预测值分别为77.6%、74.6%、79.8%、73.5%、80.7%。超声光散射成像技术联合彩色多普勒超声诊断乳腺癌的准确度、敏感度、特异度、阳性预测值和阴性预测值分别为89.7%、95.5%、85.4%、83.1%、96.2%。DOT联合彩色多普勒超声与单独DOT或单独彩色多普勒超声诊断乳腺疾病的准确度差异有统计学意义。结论:超声光散射成像技术联合应用彩色多普勒超声可提高乳腺癌诊断的准确度,为临床医生早期治疗奠定基础。

Objective：Investigating the diagnostic value combining of doppler ultrasound and diffuse optical tomography in breast cancer.Methods：Choose 156 breast neoplasms of 103 women.Conventional ultrasound examination measured the grades of blood flow,and diffuse optical tomography measured maximum hemoglobin concentration.Results：The accuracy,sensitivity,specificity,positive predictive value and negative predictive value in diagnosing breast cancer using diffuse optical tomography were 76.9％,89.6％,67.4％,67.4％,89.6％.The accuracy,sensitivity,specificity,positive predictive value and negative predictive value in diagnosing breast cancer using doppler ultrasound were 77.6％,74.6％,79.8％,73.5％,80.7％.The accuracy,sensitivity,specificity,positive predictive value and negative predictive value in diagnosing breast cancer combining doppler ultrasound and diffuse optical tomography were 89.7％,95.5 ％,85.4％,83.1％,96.2％.Conclusion：Combining doppler ultrasound and diffuse optical can improve the sensitivity of diagnosing breast cancer.