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口服抗高血压药10950张处方分析 被引量:10

Analysis of 10 950 prescriptions of antihypertensive drugs
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摘要 目的 了解出院患者口服抗高血压药的使用情况.方法 采用回顾性分析方法,随机抽取2013年1-12月首都医科大学附属北京安贞医院出院患者的高血压药物处方10 950份,对处方中口服抗高血压药的种类、用量、联合用药情况进行统计分析,并计算用药频度和药物利用指数.结果 使用频次较多的抗高血压药分别是钙通道阻滞药[81.87% (8 965/10 950)]、β受体拮抗药[47.80%(5 234/10 950)]、血管紧张素Ⅱ受体拮抗剂[46.61%(5 104/10 950)];硝苯地平、美托洛尔和氨氯地平是处方量最多的药物品种,分别占40.35%(4 418/10 950)、38.28%(4 192/10 950)和29.87%(3 271/10 950);29种口服抗高血压药中,有26种药物的药物利用指数接近1;口服抗高血压药联合应用占总处方数的52.86%(5 162/10 950).结论 本院住院患者口服抗高血压药用药情况总体较好,但个别药物仍存在不合理用药问题. Objective To provide evidence for rational clinical use ofantihypertensive drugs.Methods Totally 10 950 medical records in 2013were randomly selected; the dosage,the combination therapy defined daily doses (DDDs) and the drug utilization index(DUI) were observed.Results The most frequently used drugs were calcium channel blocker (CCB) [81.87% (8 965/10 950)],β-receptor blocking(β-RB) [47.80% (5 234/10 950)] and angiotensin receptor blockers (ARB) [46.61% (5 104/10 950)] ; nearly 26 kinds showed DUI value close to 1 ; the combined prescription was 52.86% of all prescriptions.Conclusion There is a good condition regarding using oral antihypertensive drugs; however,some antihypertensive drugs are used irrationally.
出处 《中国医药》 2015年第1期119-121,共3页 China Medicine
关键词 抗高血压药 限定日剂量 药物利用 合理用药 Oral antihypertensive drugs Defined daily dose Drug utilization Rational drug use
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