摘要
以麻鸭为动物模型,测定鸭坦布苏病毒感染后鸭的T 淋巴细胞增殖转化能力.结果显示鸭坦布苏病毒感染的试验组鸭外周血淋巴细胞刺激指数呈先上升后下降再回升的趋势,其中于第3d试验组淋巴细胞刺激指数极显著高于对照组（P〈0.01）,于第5d下降至对照组水平,于第7、15d显著低于对照组（P〈0.05）,于第21d回升至接近对照组水平.以上结果表明,鸭坦布苏病毒感染鸭后7～21d会抑制鸭T 淋巴细胞的增殖转化功能,造成鸭T 淋巴细胞的免疫抑制.
In this study,Sheldrake was used as the animal model,and we tested the proliferation of its T lymphocyte after infected by duck Tembusu virus.The result showed that after duck Tembusu virus infection, stimulation index of peripheral blood lymphocyte of test group increased first and then decreased,and recovered again.Lymphocyte stimulation index of test group was significantly (P <0.01)higher than that of control group at 3dpi (day post-infected),and then decreased to the level of control group at 5dpi,and was significantly lower (P <0.05)than that of control group at 7dpi and 15dpi,and then recovered to the level of control group at 21dpi.The result indicated that duck Tembusu virus infection could cause the duck T lymphocyte immune suppression during 7 dpi to 21 dpi.
出处
《福建农业学报》
CAS
2014年第11期1062-1065,共4页
Fujian Journal of Agricultural Sciences
基金
国家自然科学基金项目(31201936)
国家现代农业产业技术体系建设专项(CARS-43)
福建省种业创新与产业化工程项目(2014)
关键词
鸭坦布苏病毒
淋巴细胞增殖
刺激指数
duck Tembusu virus
lymphocyte proliferation
stimulation index
