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VEGF在子宫内膜异位症中的表达及临床意义 被引量:1

Expression and clinical significance of VEGF protein and mRNA in Endometriosis
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摘要 目的探讨子宫内膜异位症组织中VEGF 的表达水平及临床意义.方法:采用RT-PCR 的方法对内异症患者和正常内膜中VEGF 的表达进行测定.结果:VEGF 在异位内膜、在位内膜中的表达显著高于正常内膜(P〈0.05);其在异位内膜的表达显著高于在位内膜(P〈0.05).结论:VEGF 在EMs 中的表达水平比正常内膜显著增高,由此推测VEGF 与EMs 的发生、发展可能密切相关. Objective To investigate the expression of VEGF mRNA in endometriosis.Methods: To determine the expression of VEGF in the normal endometrium、eutopicendometrium in endometriosisi and ectopic endometrium in endometriosis by RT-PCR..Results: The expression level of VEGF in ectopic and eutopic endometrium of endometriosiswas markedly higher than that in control group(P〈0.05).It in the ectopic endometrium of endometriosis was markedly higher than that in the eutopic endometrium of endometriosis(P〈0.05).Conclusion: .The expression level of VEGF in endometriosis was markedly higher than that in the normal endometrium ,Statiscal analysis revealed that VEGF wereassociated with the occurrence and development of endometriosis.
出处 《河南中医》 2014年第B11期127-127,共1页 Henan Traditional Chinese Medicine
基金 邯郸市科技发展计划项目(项目编号1223108090)
关键词 子宫内膜异位症 异位内膜 在位内膜 VEGF endometriosis eutopic endometrium ectopic endometrim VEGF
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