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甲泼尼龙或地塞米松佐治大叶性支原体肺炎的疗效比较

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摘要 目的观察甲泼尼龙与地塞米松辅助治疗大叶性支原体肺炎的疗效比较,为临床工作提供参考.方法:选择大叶性支原体肺炎患儿40例,随机分为对照组和观察组各20例.两组患儿均给予阿奇霉素抗感染、联合退热、止咳、雾化等对症治疗.其中一组给予小剂量甲泼尼龙1~2 mg/(kg·d)静滴,连用3~5 d;另一组给予地塞米松[0.1~0.2 mg /(kg·d)]静滴,连用3~5 d.观察并比较两组患儿体温恢复时间、住院时间、治疗1周及2周胸片炎症基本吸收例数.结果:两组患儿体温恢复时间和住院时间比较,差异无统计学意义(P〉0.05).治疗1周、2周两组胸部X线提示炎症基本吸收比较,差异无统计学意义(P〉0.5).结论:甲泼尼龙和地塞米松在减少大叶性支原体肺炎的发热持续时间和住院时间缩短等方面差异未见显著性,对于肺部炎症的吸收情况差异未见显著性.但甲泼尼龙抗炎作用强,副作用小,在疗效相当的基础上,甲泼尼龙佐治大叶性支原体肺炎在临床上更值得推广.
作者 高宇 蔡斌
出处 《河南中医》 2014年第B11期184-185,共2页 Henan Traditional Chinese Medicine
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