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Tei指数联合NT-pro-BNP评估室间隔缺损患儿介入治疗术前左心功能的临床研究

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摘要 目的探讨检测血清NT-pro-BNP 浓度结合左心室Tei 指数评估室间隔缺损患儿介入治疗术前左心功能的临床应用价值.方法:选择室间隔缺损(VSD)患儿60 例作为实验组,男(35)例,女(25)例;年龄(8.324±4.367)岁.同期小儿内科住院无先天性心脏病患儿20 例作为对照组.将心功能分为四级,于介入治疗前用多普勒超声心动图测量左心室Tei 及左心室射血分数,采用酶联免疫吸附法(ELISA)检测血浆氨基末端脑利钠肽(N-pro-BNP)浓度.结果:患儿血清N-pro-BNP浓度、左心室Tei 指数在心功能0 级、Ⅰ 级、Ⅱ 级、Ⅲ 级呈逐渐升高趋势,左心室射血分数呈逐渐减低趋势,且方差分析显示各组间均数比较,差异有统计学意义(P〈0.01).结论:Tei 指数与血浆N-pro-BNP 浓度评价心室功能的相关性良好,能够迅速、准确评估室间隔缺损患儿介入治疗术前心功能,具有临床推广应用价值.
出处 《河南中医》 2014年第B11期248-248,共1页 Henan Traditional Chinese Medicine
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