期刊文献+

1例急性白血病化疗后血小板为零患者的护理

下载PDF
导出
摘要 目的急性白血病是发生于造血干细胞的恶性克隆性疾病,以发热、出血、贫血和感染为四大临床特征.虽随着治疗技术的改进,急性白血病患者获得了更高的缓解率和更长的生存期,但在诱导治疗阶段的早期死亡仍旧是临床上尚未解决的问题,而出血更是成为急性白血病早期死亡最重要的因素[1].方法:急性白血病大剂量化疗后有7-14 d 的骨髓抑制期[2],导致白细胞下降,血小板低下.血小板是人体血液中不可缺少的组成部分,正常值是100~300×109/L,它的寿命平均为8~12天,化疗后多种原因导致血小板计数结果低于参考值下限,就是血小板减少.结果:血小板主要是止血、加速凝血并维护毛细血管壁完整性的功能,因此,血小板低会直接影响到人体健康,甚至危及生命.
作者 杨桂梅
出处 《河南中医》 2014年第B11期496-496,共1页 Henan Traditional Chinese Medicine
  • 相关文献

参考文献5

二级参考文献26

  • 1Di Bona E, Avvisati G, Castaman G, et al. Early haemorrhagic mor- bidity and mortality during remission induction with or without all-trans retinoic acid in acute promyelocytic leukaemia [ J ]. Br J Haemato1,2000,108:689 - 695.
  • 2de Stefano V,Sora F, Rossi E,et al. The risk of thrombosis in patients with acute leukemia :occmTence of thronLbosis at diagnosis and during treatment[ J]. J Thromb Haemost ,2005,3 : 1985 - 1992.
  • 3de la Serna J, Montesinos P, Vellenga E. Causes and prognostic factors of remission induction failure in patients with acute promye- locytic leukemia treated with all-trans retinoic acid and idarubicin [J]. Blood,2008,111 :3395 -3402.
  • 4Raanani P, Segal E, Levi I, et al. Diffuse alveolar hemorrhage in a- cute promyeloeytic leukemia patients treated with ATRA-a mani- festation of the basic disease or the treatment [ J ]. Leuk Lympho- ma ,2000,37 : 605 - 610.
  • 5Breccia M, Avvisati G, Latagliata R,et al. Occurrence of thrombot- ic events in acute promyelocytic leukemia correlates with consistent immunophenotypic and molecular features [ J ]. Leukemia, 2007, 21:79 - 83.
  • 6Talhnan MS, Lefebvre P, Baine RM, et al. Effects of all-trans retin- oie acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibrinolysis in patients with acute promyelo- cytic leukemia[J]. J Thromb Haemost,2004,2:1341 - 1350.
  • 7Wang J, Weiss I, Svoboda K, et al. Thrombogenic role of cells un- dergoing apoptosis [ J ]. Br J Haematol, 2001 ; 115 : 382 - 391.
  • 8Falanga A ,Alessio MG,Donati MB ,et al. A new procoagulant in a- cute leukemia[ J ]. Blood, 1988,71:870 - 875.
  • 9Alimoghaddam K, Ghavamzadeh A, Jahani M. Use of Novoseven for arsenic trioxide-induced bleeding in PML [ J], Am J Hemalol, 2006,81:720.
  • 10Tapiovaara H,Matikainen S, Hurme M, et al. Induction of differ- entiation of promyelocytic NB4 cells by retinoic acid is associated with rapid increase in urokinase activity subsequently downregu- lated by production of inhibitors [ J]. Blood, 1994,83 : 1883 - 1891.

共引文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部