非过量饮酒与小肠细菌过生长的关系

The impact of non-excessive alcohol consumption on the Small intestinal bacterial overgrown

目的通过氢呼气试验探讨非过量饮酒与小肠细菌过生长之间关系.方法：收集2013-2014 年在本院行氢呼气试验的患者98 例,剔除过量饮酒后共75 例患者回顾性统计分析其年龄、性别、体重指数、谷丙转氨酶水平、甘油三酯水平、总胆固醇水平、吸烟及饮酒情况.结果：本研究中非过量饮酒者氢呼气试验阳性率为58.1%（25/43）,与无饮酒者34.3%（11/32）相比存在统计学差异（P=0.04）,并且对饮酒者饮酒频率比较发现饮酒频率增加易导致小肠细菌过生长的发生（P＊=0.019）.结论：非过量饮酒也易导致小肠细菌过生长的发生,且饮酒频率增加,阳性率也增加,说明酒精是小肠细菌过生长的高危险因素.

Objective To evaluate the association between non-excessive alcohol consum -ption and Small intestinal bacterial overgrown（SIBO） using the lactulose breath test（LBT）.Methods： 98 cases of patients underwent the LBT between 2013 and 2014 in our hospital. Without alcohol abuse, a retrospective chart review was completed for 75 consecutivepatients including age, sex, BMI, ALT,triglyceride, total cholesterol, alcohol and tobacco history.Results： This research shows that those patients who consumed non-excessive alcoholhad 58.1 % （25/43） positive LBT, compared to 34.3 % （11/32） of abstainers （P=0.008）. And the higher LBT positive rates occurred when the alcohol consumption frequency wasincreased （P=0.019）.Conclusion： Non-excessive alcohol consumption was also play an important role in the development of SIBO, and the SIBO positivity increased with the raise ofalcohol consumption frequence. So the alcohol might be a strong risk factor for SIBO.