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放疗联合替莫唑胺治疗老年人胶质瘤母细胞瘤的疗效分析

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摘要 目的对老年恶性脑胶质瘤术后患者行常规放疗联合口服化疗药物替莫唑胺(TMZ)的疗效、安全性进行分析.方法:收集了2000年1月至2013年1月就诊于我科的35名脑胶质母细胞瘤术后老年患者,均应用适形放射治疗,15名患者同步给予患者替莫唑胺胶囊化疗,有5名患者继续替莫唑胺胶囊辅助化疗大于6个周期.对治疗的疗效、治疗相关副反应进行分析.结果:中位随访时间为12.1个月,患者中位总生存期(OS)为12.2个月,1年生存率为58%,单独放疗组中位OS为8.1个月,1年生存率为43%.所有患者均未出现Ⅲ-Ⅳ级毒副反应,耐受性良好.结论:常规放疗同步及辅助化疗治疗老年人胶质母细胞瘤的疗效确切,安全、可行.
出处 《中医学报》 CAS 2014年第B12期323-323,共1页 Acta Chinese Medicine
基金 辽宁省科技攻关课题(NO:2012225008)
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