慢性每日头痛的研究进展

Research Progress on Chronic Daily Headache

慢性每日头痛(CDH)是临床常见的频繁发作的慢性头痛。CDH根据初始头痛类型及临床表现可分为慢性偏头痛、慢性紧张性头痛、新发每日持续头痛和持续性偏侧头痛。CDH多由发作性头痛转化而来,肥胖、基线头痛频率、精神共患疾病等均是头痛慢性转化的危险因素。原发性CDH的发病机制与三叉神经感觉神经元敏感化有关。鉴于CDH给患者带来持久的痛苦,其防治十分重要。对于CDH的治疗,除了药物外,还应预防危险因素,杜绝药物过量,并注重生活习惯和心理卫生的改善。本文就CDH的流行病学、发病机制及诊治研究进展进行综述。

Chronic daily headache（ CDH） is a commonly seen chronic headache with frequent attacking. CDH can be classified into chronic migraine,chronic tension-type headache,new daily persistent headache and persistent hemicrania based on the initial type of headache and clinical manifestation. Most CDH is transformed from paroxysmal headache,and its risk factors include obesity,baseline headache frequency and psychiatric comorbidity. The pathogenesis of primary CDH is closely related to pain sensitization of trigeminal sensory neuro. The prevention and treatment of CDH is vitally important because it brings continuous suffering to patients. Besides drug therapy,preventing risk factors and drug overdose are also important. The improvement of life quality and mental health should also be emphasized in the treatment of CDH. This article summarizes the research progress of CDH in terms of epidemiology,pathogenesis,diagnosis and treatment.