高致病性猪蓝耳病弱毒疫苗与灭活疫苗的免疫效果评估试验

Evaluation of Highly Pathogenic PRRS Attenuated Vaccine and Inactivated Vaccine

在相同饲养条件下,对35日龄仔猪分别使用高致病性猪蓝耳病弱毒疫苗与灭活疫苗进行免疫接种。在接种当天、接种后28d、58d分别检测高致病性猪蓝耳病免疫抗体水平。结果显示,使用弱毒疫苗免疫的试验猪,其高致病性猪蓝耳病抗体上升速度和抗体水平均优于使用灭活疫苗的试验猪。弱毒疫苗可在接种后21～28d产生免疫力,免疫期为4个月。猪繁殖与呼吸综合征流行地区应该首先考虑使用弱毒疫苗。

35 day-old piglets were respectively immunized with highly pathogenic PRRS attenuated vaccine and invactivated vaccine..The immune antibodies were checked,which were conlected from 0,28,58 day-post-immunization（dpi）. The results showed that after using PRRS attenuated vaccine,the immune antibodies to PRRS were induced higher and faster than that of inactivated one. And the attenuated vaccine could induce immunity 21 ～ 28 dpi, persisting to 4 months. So porcine reproductive and respiratory syndrome virus epidemic areas should firstly consider using attenuated vaccine.