CATS和Cell Saver自体血回收机对骨科手术中回收血液流变学及其质量的影响

Influence of CATS and Cell Saver on hemorheology and blood quality of intraoperative cell salvage in orthopaedic surgery

目的分析2种自体血回收机在骨科手术中的回收血液流变学指标[红细胞最大变形指数(DImax)、聚集指数(AImax)、渗透脆性、红细胞压积(Hct)、血红蛋白(Hb)]和血液质量(Hct、Hb、血电解质及pH值)以及自体血回输后患者体内Hct、Hb、血电解质及pH值的变化,为临床自体血回收提供参考。方法骨科手术患者76例分为A组(使用CATS)和B组(使用Cell Saver);采集自体血检测DImax、AImax、渗透脆性、Hct、Hb、血电解质、pH值及输自体血前、后、术后24h取患者静脉血并分别检测Hct、Hb、血电解质、pH值。结果 A组DImax低于B组(P<0.05),两组与参考值比较差异均无统计学意义(P>0.05);两组AImax比较差异无统计学意义(P>0.05),但均明显低于参考值。A组红细胞渗透脆性曲线较B组右移。各指标与其对应参考值比较差异均有统计学(P<0.05)。A组自体血Hct、Hb、K+明显高于B组,Na+明显低于B组,各指标与其对应参考值比较差异均有统计学意义(P<0.05)。两组自体血pH值均偏碱性。输自体血前、后即刻、术后24h两组间机体血Hct、Hb、K+、Na+、pH值差异均无统计学意义(P>0.05)。两组输自体血后机体血Hct与Hb、Na+明显高于输自体血前(P<0.05)。结论骨科手术中2种自体血回收机所得到的自体血在流变学指标及其血液质量皆无明显差异,自体血回输后对机体内环境也无明显影响,2种自体血回收机的性能较为安全。

Objective To observe recycle homorheology index of two autologous blood recover machines in orthopedic operation,including maximum deformation index（DImax）,aggregation index（AImax）,osmotic fragility,hematocrit（Hct）,hemoglobin（Hb）,blood electrolytes and pH value,the changes of in vivo Hct,Hb,blood electrolyte and pH value after the autotransfusion to provide references for rational clinical use of cell salvage.Methods Seventy-six patients were randomly divided into group A（CATS）and group B（Cell Saver）,38 cases in each group.Autologous test of DImax,AImax,osmotic fragility,Hct,Hb,blood electrolytes,pH value and Hct,Hb,osmotic fragility,pH value of patients before and after autotransfusion,24 hafter operation,used to determine the in vivo salvaged were measured.Results DImax of group A were lower than that of group B with no difference（P〈0.05）;AImax of both groups had no different（P〉0.05）,but was lower than the reference value.RBC osmotic fragility curve shifted to the right in group A,each index was significantly lower than its reference value（P〈0.05）.The in vivo Hct,Hb,K^＋of group A were significantly higher than that of group B,Na^＋level of group A was lower than of group B,each index had significantly difference with its reference value（P〈0.05）.pH value of both groups was slightly alkaline.The in vivo Hct,Hb,K^＋,Na^＋level and pH value of both groups had no difference at the point of before and immediately after autotransfusion and 24 hpostoperatively,there were no statistically difference（P〉0.05）.The in vivo Hct of both groups after autotransfusion were significantly higher than before（P〈0.05）.Conclusion The hemorheology index and quality of salvaged blood acquired from these two cell salvage systems in orthopaedic operation have no obvious differences.The function of these two kinds of cell salvage systems is safer and reliable.