手助腹腔镜与全腹腔镜手术治疗结直肠癌疗效比较的Meta分析

Hand-assisted laparoscopic versus laparoscopic-assisted surgery radical resection of colorectal cancer: a Meta analysis

目的:评价手助腹腔镜(HALS)与纯腹腔镜手术(LAS)两种术式治疗结直肠癌的疗效及安全性。方法:选取发表于2000年—2013年的关于手助腹腔镜与纯腹腔镜手术两种术式治疗结直肠癌的比较性研究文献,使用RevMan 5.0软件进行数据处理。结果:Meta分析纳入了7篇文献,共计650例患者,其中手助腹腔镜手术治疗320例,全腹腔镜手术治疗330例。Meta分析结果提示手助腹腔镜组手术时间较短(P<0.000 01),出血量较少(P=0.000 3),在清扫淋巴结数目(P=0.28)、肠功能恢复时间(P=0.22)、术后住院天数(P=0.63)、术后并发症(P=0.49)方面,手助腹腔镜组与全腹腔镜组之间差异无统计学意义。结论:手助腹腔镜与全腹腔镜手术在结直肠癌治疗上同样安全有效,甚至在有些方面显示出优势。

Objective ：To compare outcomes of hand - assisted laparoscopic （HALS） and laparoscopic - assisted （ LAS ） surgery radical resection of eoloreetal cancer using Meta analysis. Methods ： Retrieved clinical trials comparing hand - assisted laparoseopic with laparoseopie - assisted surgery radical resection of colorectal cancer published from 2000 to 2013. Data were analyzed by Rev - Man 5.0 software. Results ： Seven clinical trials were included in this analysis. These studies included a total of 650 patients：320 treated with hand- assisted laparoscopic and 330 treated with Laparoscopie -assisted surgery. The Meta statistical showed as follow：hand - assisted laparoseopic was more less in operation time （P 〈 0. 000 01 ） and surgical blood loss （ P = 0.0 0 0 3 ） . There was no statistical difference between the two techniques in the number of lymph nodes （ P = 0.28 ）, bowel function recovery time （P = 0.22）, post - operative stay in hospital （P = 0.63 ） and postoperative complications （ P = 0.49 ）. Conclusion ： For the treatment of colorectal cancer, hand - assisted laparoscopie is more safe and effective as Laparoscopic - assisted surgery.