不同降脂方法对稳定性心绞痛患者血脂达标后的疗效观察

To observe the lowing-hpid therapy for patients with stable angina pectoris who had achieved the blood-fat goal

目的：探讨血脂达标后的降脂方法.方法：选择2012年1月-2014年3月低密度脂蛋白-胆固醇（LDL-C）＜ 2.6 mmol/L的75岁以下的冠心病患者94例,随机分为实验组（瑞舒伐他汀,每晚10 mg）47例和对照组（瑞舒伐他汀,隔晚10 mg）47例,随访1～6个月,观察LDL-C水平的变化情况.结果：实验组及对照组在治疗1个月后及治疗6个月后的LDL-C水平无明显变化,两组比较差异无统计学意义（P＞0.05）;随着治疗时间的延长,各个治疗时间点之间,差异也无统计学意义（P＞0.05）.结论：血脂达标后,隔晚服用常规剂量的瑞舒伐他汀,可以有效地稳定LDL-C水平.

Objective：To discusses the owing- hpid method for who had attained the blood -fat goal. Methods：Nighty - four stable angina pectoris cases were elected whose（ low density lipoprotein） LDL- C level lower than 2.6 mmol/L, and age lower than 75 years old during January 2012 to March 2014. All patients were divided into two groups, routine group who has 10 mg rosuvastatin every night in experimental group （47 cases）, and trial group instead 10 mg rosuvastatin every other night in control group （ 47 cases） , followed up 1 - 6 months, to observe the level of LDL - C. Results ： The change in LDL - C level, the experimental group and the control group after 1 months of treatment and treatment had no significant change after 6 months, the comparison between the two drug groups, no significant difference （P 〉 0.05 ） ;with the extension of treatment time, between each treatment time point, also no significant difference（ P 〉 0.05 ）. Conclusion：For those who had attmned LDL - C goal has 10 mg rosuvastatin alternate night can decrease the LDL - C level effetely.