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肺泡表面活性物质联合鼻塞式持续气道正压通气治疗早产儿呼吸窘迫综合征的效果分析 被引量:11

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摘要 目的 分析比较肺泡表面活性物质联合鼻塞式持续气道正压通气对预防早产儿呼吸窘迫综合征的效果.方法 选取我院新生儿监护室2013年1-12月早产儿呼吸窘迫综合征60例,随机分为A组和B组,每组均为30例,B组采用常规方法治疗,A组采用肺泡表面活性物质联合鼻塞式持续气道正压通气治疗,比较两组治疗效果.结果 A组治疗6h后氧分压为(77.61±1.86) mmHg(1mmHg=0.133 kPa),高于B组[(73.20±1.78) mmHg];二氧化碳分压为(43.55±1.56) mmHg,低于B组[(46.77±1.73) rnmHg],差异均有统计学意义(t值分别为2.457、3.902,P均<0.05);A组治疗后1例出现呼吸机相关肺炎,2例(6.7%)出现气压伤,并发症发生率低于B组[26.7%(8/30)、30.0%(9/30)],差异有统计学意义(P值分别为0.037、0.042);A组住院时间为(21±4)d,短于B组[(32±6)d],差异有统计学意义(P=0.030).结论 早产儿呼吸窘迫综合征发病率较高,临床上采用肺泡表面活性物质联合鼻塞式持续气道正压通气治疗效果理想,能够有效地缩短患者住院时间,提高临床治愈率,值得推广使用.
出处 《中国综合临床》 2014年第12期1337-1338,共2页 Clinical Medicine of China
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