从不同观察指标综述针灸治疗失眠症的基础研究进展

Basic research advances of insomnia summarized from different observed indicators by acupuncture treating

本文主要从三个方面综述了针灸治疗失眠症的基础研究进展。临床心理量表方面,失眠症显示匹兹堡睡眠质量指数、抑郁自评量表、焦虑自评量表等评分异常,而针灸均表现良好的调节作用;动物神经行为学方面,失眠大鼠显示空间工作记忆功能损害,而针灸均表现良好的改善空间记忆的依据;睡眠机制方面,对失眠症显示5-羟色胺、γ-氨基丁酸等神经递质以及白介素、前列腺素D2、褪黑素等睡眠因子的异常,针灸均显示良性的调节作用。文献显示针灸治疗失眠症方法丰富多彩,也证明针灸是治疗失眠症的有效方法。同时,本文也提出研究中存在的一些不足和值得注意的方面。

This paper mainly summarized the basic research advances of insomnia of acupuncture treatment from three basic aspects. In terms of clinical psychological scale, insomnia displayed PSQI, SDS, SAS and other abnormal scores, while acupuncture showed good regulation. In terms of animal neu-robehavioral, insomnia rats showed spatial working memory dysfunction, and acupuncture showed a good basis of improving spatial memory; In terms of sleep mechanisms, acupuncture usually showed a benign regulation to the abnormal neurotransmitter, such as 5-HT, GABA etc and the abnormal sleep factors, such as interleukin, PGD2, melatonin etc, in insomnia rots. Literature showed that there were a variety methods of acupuncture treating insomnia. It also proved that acupuncture was an effective treatment for insomnia. Meanwhile, the paper also proposed the existence of a number of aspects of research gaps and noteworthy.