MSCT测量胆囊周围间隙在评估肝硬化患者肝功能储备中的意义

The Value of Peripheral Space of Gallbladder Measured by MSCT in Assessment of Liver Function of Patients with Cirrhosis

目的研究MSCT测量胆囊周围间隙在评估肝硬化患者肝功能储备中的意义。方法收集临床诊断为肝硬化并行腹部CT检查的101例患者为观察组,按肝功能Child-Pugh分级A级57例,B级27例,C级17例;并收集同期行上腹部CT增强扫描的健康体检者或者其他系统疾病的患者50例作为对照组。应用CT扫描并重建肝、脾、胆图像,测量各组患者的肝、脾体积及其比值和胆囊周围间隙,按不同的肝功能分级对上述指标进行对比分析。结果观察组患者的肝体积、肝脾体积比值均与肝功能分级呈负相关(P<0.05);观察组患者的胆囊周围间隙明显宽于对照组(P<0.05),其宽度与肝功能损害程度呈正相关(P<0.05),与肝体积、肝脾体积比和肝功能储备状态呈负相关(P<0.05)。结论胆囊周围间隙是评估肝硬化患者肝功能储备状态的简单有效指标。

Objective To investigate the value of Peripheral space of gallbladder measured by multi-slice spiral CT （MSCT） in assessment of liver function of Patients with Cirrhosis. Methods 101 patients with cirrhosis took MSCT scanning of abdomen were classified into 57 cases of level A, 27 cases of level B and 17 cases of level C according to Child-Pugh classification. 50 cases of healthy physical examinees and patients with other diseases （control group） took MSCT scanning in the same period were as the control group. We scanned livers, spleens and gallbladders by multislice spiral CT, reconstructed 3D views of organs. The liver and spleen volume, its ratio and peripheral space of gallbladders were measured. The above indicators were comparative analysis according the liver function classification. Results The liver volume, liver-spleen volume ratio in observation peripheral 0.05）, the correlation group showed negative correlation with the liver classification （P〈0.05）. The space of gallbladder in observation group was wider than that in control group （P〈 width had positive correlation with liver damage degree （P〈0.05） and negative with liver volume, liver-spleen volume ratio and hepatic functional reserve （P〈0.05）. Conclusion Peripheral space of gallbladder is a simple and effective tool to evaluate liver function of cirrhosis patients