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联合用药在抗肿瘤纳米递药系统中的应用 被引量:5

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摘要 多药联合应用已成为临床上治疗肿瘤的首选方案。纳米药物传递系统可改善抗肿瘤药物的体内分布及药动学性质,提高药物对特定靶点的选择性,达到高效低毒的治疗目的。文中简要综述纳米递药系统在抗肿瘤联合用药方面的研究进展、面临的挑战及发展趋势。
作者 许秀丽 黄园
出处 《华西药学杂志》 CAS CSCD 北大核心 2014年第6期720-722,共3页 West China Journal of Pharmaceutical Sciences
基金 国家自然科学基金资助项目(批准号:81072600)
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  • 1Logman JFS, Heeg BMS, Botteman MF,et al. Economic evaluation of zoledronic acid for the prevention of osteoporotic fractures in postmenopausal women with early - stage breast cancer receiving aromatase inhibitors in the UK [ J ]. Annals Oncology, 2010,21 (7) :1529 - 1536.
  • 2Liu XY, Mc TANT, Lee HS. In vitro cytotoxicity of Stealth lipo- somes co - encapsulating doxorubicin and verapamil on doxorubi- cin - resistant tumor cells [ J ]. Biol Pharm Bull, 2005,28 ( 5 ) : 822 - 828.
  • 3Shaikh IM,Tan KB, Chaudhury A, et al. Liposome co - encapsu- lation of synergistic combination of irinotecan and doxorubicin for the treatment of intraperitnneally grown ovarian tumor xenograft [J]. J Control Rel,2013,172(3) :852 -861.
  • 4Zucker D, Barenholz Y. Optimization of vincristine - topotecan combination--Paving the way for improved chemotherapy regi- mens by nanoliposomes [ J ]. J Control Rel, 2010,146 ( 3 ) : 326 - 333.
  • 5Zhang Y,Wang J,Bian D,et al. Targeted delivery of RGD - mod- ified liposomes encapsulating both eombretastatin A -4 and doxo- rubiein for tumor therapy:In vitro and in vivo studies [ J ]. Eur J Pharmaceut Biopharmaeeut ,2010,74 ( 3 ) :467 - 473.
  • 6Bilim V. Technology evaluation: PK1, Pfizer/Cancer Research UK [ J]. Cur Opinion Moleeul Therap,2003,5 ( 3 ) : 326 - 330.
  • 7Sapra P, Mehlig M, Malaby J,et al. EZN - 2208, a novel polyeth- yleneglycol - SN38 conjugate, has potent antitumor activity in a panel of human tumor xenografts [ C ]. American association of cancer research annual meeting poster,2007:1494.
  • 8Vieent MJ, Greco F, Nieholson RI, et al. Polymer therapeutics designed for a combination therapy of hormone - dependent canc- er[J]. Angewandte Chemie,2005,117(26) :4129 -4134.
  • 9Greeo F, Vieent M J, Gee S, et al. Investigating the mechanism of enhanced eytotoxieity of HPMA copolymer - Dox - AGM in breast cancer cells [ J ]. J Control Rel,2007,117 ( 1 ) :28 - 39.
  • 10Lammers T, Subr V, Ulbrich K, et al. Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers [J ]. Biomater, 2009,30 (20) : 3466 - 3475.

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