产后抑郁症相关影响因素的研究

Risk factors of postpartum depression

目的探讨产后抑郁症的影响因素。方法对妊娠晚期的293例孕妇进行社会人口学、匹茨堡睡眠质量量表、爱丁堡产后抑郁量表评定,并使用DSM-IV-TR轴I障碍结构式访谈患者版(SCID-I/P)进行抑郁症诊断,在产后3个月再次进行量表填写及结构式访谈诊断,最终纳入研究223例,采用非条件logistic回归模型进行相关性统计检验。结果本研究产后抑郁症的总患病率为9.4%。在校正其他影响因素后,年龄、家庭收入、婚姻满意度、睡眠质量与产后抑郁症有显著相关性,其中,年龄、睡眠质量评分(分数越高睡眠质量越差)与产后抑郁症呈正相关,家庭收入、婚姻满意度与产后抑郁症呈负相关,且妊娠晚期睡眠质量评分与产后抑郁症呈正相关。结论年龄、妊娠晚期主观睡眠质量差、家庭收入、婚姻满意度是产后抑郁症的危险因素。

Objective To investigate the risk factors of postpartum depression. Methods Two hundred and ninety three women with uncomplicated pregnancies in their last pregnancy trimester were enrolled in the study. The demographic character-istics were surveyed with questionnaire, the psychological status was evaluated with Pittsburgh Sleep Quality Index and Edin-burgh Postnatal Depression Scale. Depression was diagnosed with Structured Clinical Interview for DSM- IV- TR Axis I Disorders Patient Edition （SCID- I/P）. The participants were evaluated again 3 months after delivery, final y 223 cases were included in the study. The correlations between postpartum depression and various parameters were analyzed with Logistic model. Results The mean age of participants was 26.5±3.0 y （21-36）, and mean gestation weeks were 31.8±1.6 （28-36）. The total prevalence of postpartum depression was 9.4%. After control ing other factors, postpartum depression was positively correlated with age and sleep quality index （bad sleep with a high score） , and negatively correlated with high income and satisfactory with marriage. Be-sides, sleep quality index score was associated with postpartum depressive symptoms. Conclusion Bad subjective sleep quali-ty in the third trimester of pregnancy is a risk factor for postpartum depression. Early intervention of bad sleep quality may prevent postpartum depression.