壳聚糖的改性及其自由基清除性能

Modification of Chitosan and Free Radical Scavenging Activities

介绍了不同相对分子质量、不同脱乙酰化度和O-改性壳聚糖的制备方法,综述了壳聚糖清除自由基性能的研究进展.总结了相对分子质量、脱乙酰度和O-修饰等因素对壳聚糖及其衍生物清除自由基的影响.

Chitosan and its derivatives are unique cationic copolymer of glucosamine and N-acetyl-glucosamine. They have drawn much attention in various fields, including pharmaceutical, biomedicine, water treatment, cosmetics, agriculture, and food industry, due to their useful characteristics such as biorenewabilty, biodegradability, biocompatibility, bioadhesivity and nontoxicity. This paper introduced the synthetic method of different molecular weight, different degree of deacetylation and O-modified chitosan. Moreover, it revewed the recent free radical scavenging activities of chitosan and its derivatives and discussed in brief the roles molecular weight, degree of deacetylation and O-modification played in free radical scavenging.