半夏泻心汤治疗反流性食管炎50例

BanXia XieXinTang in Treating 50 Cases of Reflux Esophagitis

目的:观察半夏泻心汤治疗反流性食管炎的临床疗效。方法:将100例反流性食管炎患者随机分为观察组、对照组各50例。2组均给予西药常规治疗:奥美拉唑胶囊,20 mg/次,2次/d,口服;氟哌噻吨美利曲辛片,10mg/次,1次/d,口服。观察组同时给予半夏泻心汤,1剂/d,水煎分服。2组均以治疗1个月为1个疗程,治疗1个疗程后观察疗效。结果:治愈率观察组为78.00%,对照组为52.00%,2组相比差异有统计学意义(P<0.05)。总有效率观察组为96.00%,对照组为80.00%,2组相比差异有统计学意义(P<0.05)。吞酸、嗳气、脘胁胀痛、呃逆等症状2组治疗后均明显缓解,与治疗前比较差异有统计学意义(P<0.05),治疗后组间比差异有统计学意义(P<0.05)。结论:半夏泻心汤治疗反流性食管炎临床疗效显著,可显著改善临床症状。

Objective：To find out curative effects of BanXia XieXin Tang in the treatment for reflux esophagi-tis. Methods：One hundred patients were randomized into the observation group and the control group. Both groups were given with routine treatment of western medicine：omeprazole capsule, 20mg each time, twice per day, orally;flupentixol and melitracen tablets, 10 mg each time, once per day, by mouth. The observation group took BanXia XieXin Tang, one dose each day, water decocted. One month was one course of the treatment, curative effects were observed after one course of the treatment. Results： Cure rate of the observation group was 78.00%, higher than 52.00%of the control group with significant difference （P〈0.05）. Total effective rate of the observation group was 96.00%, superior to 80.00%of the control group with notable difference （P〈0.05）. The symptoms including acid re-gurgitation, belching, distending pain of the abdomen, hiccup and others were relieved obviously after treating in both groups, the difference had statistical meaning compared with before treating （P〈0.05）, the difference demon-strated statistical meaning between both groups （P〈0.05）. Conclusion：BanXia XieXin Tang is effective in the treat-ment for reflux esophagitis, and it could improve clinical symptoms signficantly.