符合线路SPECT/CT融合图像对全身骨显像单发“热区”鉴别诊断的临床价值

The diagnosis value of whole body bone imaging with coincidence SPECT/CT fusion imaging for solitary“hotspots”

目的探讨符合线路单光子发射计算机断层成像术(SPECT)/CT融合图像对全身骨显像单发"热区"鉴别诊断的临床价值。方法对50例恶性肿瘤患者全身骨显像单发"热区"进行符合线路SPECT/CT检查。通过与病理学检查、CT、MRI检查及6个月以上随访的结果进行比较,计算SPECT、同机CT及SPECT/CT的灵敏度、特异度及准确性。结果 SPECT显像诊断的灵敏度、特异度、准确性分别为94%、23%、63%;同机CT的灵敏度、特异度、准确性分别为47%、87%、66%;SPECT/CT的灵敏度、特异度、准确性分别为95%、80%、88%。SPECT/CT诊断的特异度及准确性显著高于SPECT(P<0.05),同时灵敏度及准确性显著高于同机CT(P<0.05)。结论符合线路SPECT/CT融合图像可显著提高对骨显像单发"热区"诊断的灵敏度、特异度及准确性,具有较高的临床应用价值。

Objective To evaluate the differentiating diagnosis value of coincidence SPECT/CT fusion imaging used in the soli-tary“hotspots”in the whole body bone imaging.Methods Fifty patients with malignancy were selected to have examination.the sensitivity,specificity and accuracy of these imaging methods were calculated by contrasting the pathology examination,CT and MRI examination,more than 6 months follow-up results between the cases.Results The sensitivity,specificity and accuracy of SPECT imaging were 94%,23%,and 63%,respectively,and that of CT were 47%,87%,66%;the sensitivity,specificity and accu-racy of SPECT/CT were 95%,80%,88%,respectively.The specificity and accuracy of SPECT/CT was significantly higher than SPECT（P〈0.05）and its sensitivity and accuracy was higher than that of CT（P〈0.05）.Conclusion Coincidence SPECT/CT hy-brid imaging could raise the sensitivity,specificity and accuracy of diagnosis of solitary“hotspot”in whole bone imaging,which is of high clinical application value.