慢性阻塞性肺疾病合并侵袭性肺曲霉菌病的研究进展

Research Progress on Chronic Obstructive Pulmonary Disease Complicated with Invasive Pulmonary Aspergillosis

近年来,慢性阻塞性肺疾病(COPD)合并侵袭性肺曲霉菌病(IPA)发病率不断增高,该类患者预后差、病死率高,早期诊断、及时治疗是改善其预后的重要措施。本文结合相关文献对COPD合并IPA的发病机制、临床特征、实验室检查、诊断及治疗等进行综述,为临床医生早期诊断和及时治疗该病提供参考。

In recent years, the morbidity of chronic obstructive pulmonary disease （COPD） complicated with inva-sive pulmonary aspergillosis （ IPA） increased gradually , and its prognosis is poor , fatality rate is high.Early diagnosis , timely treatment is an important measure to improve the prognosis.Therefore, this paper summarized the pathogenesis , clinical charac-teristics, laboratory examinations , diagnosis and treatment of COPD complicated with IPA based on relevant literatures , so as to help clinical doctors′early diagnosis and timely treatment .