时间药理学与合理用药分析

Analysis of time pharmacology and rational drug use

目的:研究药品服用最佳时机,充分发挥药物的治疗作用,减少药物用量,降低不良反应。方法:整理、搜集药物服用时间的相关信息,并进行归纳总结。结果:可指导临床合理选择服药时间。结论:根据药动学参数的节律性变化、药物效应节律性变化和药物毒性的时间节律性选择给药时间,是达到最佳疗效的途径之一。

Objective： The best time of drug taking,give full play to the role of drug treatment,reduce drug dosage,reduce the adverse reaction. Methods： To arrange and collect the related information of drug taking time,and to summarize. Results：Taking time to guide the clinical reasonable selection. Conclusion： According to the rhythm,the pharmacokinetic parameters of the drug effect of circadian variation and drug toxicity of time rhythm selection time of administration is one of the ways to achieve the best curative effect.