诸葛菜水溶性化学成分的研究

Water-Soluble Constituents from of Seeds Orychophragmus violaceus

目的研究诸葛菜的水溶性成分。方法采用柱色谱技术对诸葛菜种子的提取物进行分离纯化,采用波谱技术结合化学方法进行结构鉴定。结果从诸葛菜种子的水溶性部位中分离得到15个化合物,分别鉴定为blumenol A(1)、3',5',5,7-四羟基二氢黄酮(2)、儿茶素(3)、槲皮素(4)、腺苷(5)、水杨酸(6)、2'-脱氧腺苷(7)、对羟基桂皮酸(8)、香草酸(9)、原儿茶酸(10)、咖啡酸(11)、丁香酸(12)、胡萝卜苷(13)、丁二酸(14)和壬二酸(15)。结论所得化合物均为首次从诸葛菜中分离得到,为该植物的化学成分分类奠定了良好的基础。

OBJECTIVE To study water-soluble constituents from the seeds Orychophragmus violaceus. METHODS The constituents were isolated and purified by silica gel chromatography repeatedly,and the structures were identified by spectral analysis and chemical methods. RESULTS Fifteen water-soluble compounds were isolated from the seeds Orychophragmus violaceus and their structures were identified as blumenol A（ 1）,3＇,5＇,5,7-tetrahydroxylflavanone（ 2）,（ ＋）-catechin（ 3）,quercetin（ 4）,adenosine（ 5）,salicylic acid（ 6）,2＇-deoxy adenosine（ 7）,p-coumaric acid（ 8）,vanillic acid（ 9）,protocatechuic acid（ 10）,caffeic acid（ 11）,syringic acid（ 12）,daucosterol（ 13）,succinic acid（ 14） and azelaic acid（ 15）. CONCLUSION All compounds are isolated from Orychophragmus violaceus for the first time. This study can establish the foundation for the classification chemical composition this plant.