中心静脉血氧饱和度监测在老年人急性左心衰病情评估中的应用研究

Clinical research of central venous blood oxygen saturation in elder patients with acute left ventricular failure

目的：探讨中心静脉血氧饱和度（ ScvO2）检测在老年人急性左心衰临床应用中是否可替代混合静脉血氧饱和度（ SvO2）监测。方法对42例老年急性左心衰患者进行监测，分析治疗前以及治疗后1 h、2 h、4 h的ScvO2、SvO2指标的参数变化情况，根据不同的预后结果对相关监测参数进行统计分析。结果无论患者是生存或是死亡，ScvO2与SvO2两者所代表的趋势是相同的。治疗前检测的ScvO2与SvO2差异无统计学意义（t＝0．867，P＞0．05），治疗后4 h两者的变化趋势也有一致性，差异无统计学意义（t＝0．681，P＞0．05）。两者的相关系数r＝0．998，且为线性关系，证实两者监测具有相同的临床应用意义。结论综合考虑患者的创伤、并发症、费用等因素，可操作性更强的ScvO2可以用来替代SvO2对老年急性左心衰患者进行临床监测。

Objective To investigate the detection of central venous oxygen saturation （ ScvO2 ） whether can＆amp;nbsp;be alternative mixed venous oxygen saturation （ SvO2 ） in elderly patients with acute left ventricular failure.Methods 42 elderly patients with acute heart failure were detected by central venous oxygen saturation and mixed venous oxy-gen saturation before the treatment and 1h,2h,4h after treatment.Then the parameters index changes were analyzed according to the prognosis.Results Whatever the prognosis of the patients were,the trend of ScvO2 and SvO2 was the same.Before the treatment,the blood oxygen saturation detected by the ScvO2 with patients was no statistical differ-ence with the ScvO2（t=0.867,P〉0.05）,and after treatment of 4h the change trend detected of both has also the consistency,no statistical difference （t=0.681,P〉0.05） The correlation coefficient r=0.998,and the relationship between ScvO2 and SvO2 confirmed the same clinical significance.Conclusion Considering the factors of trauma, complications,costs and so on,ScvO2 can be used to replace SvO2 in elderly patients with acute left heart failure.