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肿瘤细胞和亚细胞器治疗靶标的研究 被引量：1

Study of cellular and sub - cellular organelles targets on cancer therapy
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摘要 各种细胞类型和亚细胞器都是肿瘤治疗的靶标，这些靶标包括肿瘤起始细胞、肿瘤干细胞、循环肿瘤细胞、转移起始细胞、骨髓来源细胞和基质细胞等细胞类型，以及线粒体、溶酶体、内质网、胞外膜泡、中心体和核仁等亚细胞器。靶向不同肿瘤细胞群和亚细胞器的治疗增加了肿瘤靶向治疗的内容。也使肿瘤个体化治疗成为可能。 Tumor cell type and sub - cellular organelle are potential targets for cancer therapy. These tar gets have cell types including tumor - initiating cells, cancer stem cells, circulating tumor cells, metastasis - initia- ting cells, bone marrow derived cells and stromal cells, as well as sub - cellular organelles including mitochondri- a, lysosome, endoplasmic reticulum, extraeellular vesicles, centrosome and nucleolus. New targets should provide more targeted therapy and personalized therapy for patients with human cancers.
作者 张百红 岳红云
机构地区 兰州军区兰州总医院肿瘤科 兰州军区兰州总医院眼科
出处 《实用肿瘤学杂志》 CAS 2014年第6期549-552,共4页 Practical Oncology Journal
基金 2013年甘肃省自然科学基金项目（1308RJZA181）
关键词 肿瘤细胞 亚细胞器 治疗靶标 Cancer cells Sub - cellular organelles Therapeutic targets
分类号 R734.2 [医药卫生—肿瘤]
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参考文献30

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共引文献8

同被引文献25

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引证文献1

  • 1张百红,岳红云.肿瘤星球[J].实用肿瘤学杂志,2015,29(6):561-564.
实用肿瘤学杂志
2014年 第6期

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