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心肌梗死后心力衰竭患者NK细胞活性与左心室功能的相关性 被引量:4

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摘要 目的探讨心肌梗死后心力衰竭患者自然杀伤细胞(NK细胞)活性与左心室功能的相关性。方法NK细胞取自50例心肌梗死后心力衰竭患者(NYHAⅡ-Ⅳ级)以及25例健康志愿者。采用心脏超声检测左室射血分数;LDH细胞毒性检测NK细胞的杀伤活性。结果心肌梗死后心力衰竭患者左室射血分数明显低于健康志愿者(P〈0.01);心肌梗死后心力衰竭患者NK细胞数目、杀伤活性较健康志愿者明显降低(P〈0.01),NK细胞活性与心肌梗死后心力衰竭患者左室射血分数相关(R2=0.739 6,P〈0.01)。结论 NK细胞数目和活性的下降与心肌梗死后心力衰竭患者左心室功能的衰退有着密切的关系。
出处 《广东医学》 CAS CSCD 北大核心 2014年第23期3724-3726,共3页 Guangdong Medical Journal
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共引文献50

同被引文献47

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