194例HBeAg阳性HBV携带者中医证候及体质分布规律观察

Observation of TCM syndrome and constitutions distribution law of 194 cases HBe Ag positive HBV carriers

目的:观察194例HBe Ag阳性的HBV携带者中医证候及体质的分布规律,探讨病机,为中医药干预提供理论依据。方法:选择194例HBe Ag阳性HBV携带者,中医证候采用问卷调查结合高级中医师辨证进行分型,中医体质根据王琦中医体质分类法进行分类,部分患者行肝脏穿刺病理检查,将证候及体质、病理结果进行统计分析。结果:194例HBe Ag阳性的HBV携带者在症状方面以困倦乏力、尿黄、腰腿酸痛、腰腿酸软、健忘等症状显现频率较高,有证可辨者以肾虚证为主(68.4%),异常体质者中也以肾虚体质为主(22.6%),肝穿病理检查结果提示部分患者(60.5%)存在不同程度的炎症及纤维化。结论:肾虚是慢性乙型肝炎(CHB)致病的重要病机。

Objective： To observe the distribution law of 194 cases of HBeAg positive HBV carriers of TCM syndrome and constitution, to investigate pathogenesis, provide theoretical basis for the intervention of traditional Chinese medicine. Methods： Selected 194 cases of HBeAg positive HBV carriers, TCM syndrome classification based on the questionnaire survey combined with advanced TCM doctor , TCM constitution classification based on WANG-Qi＇s classification, Some patients with liver patho- logic examination, the TCM syndrome and constitution and pathological results were analyzed. Results： One hundred ninety and four cases of HBeAg positive HBV carriers had higher frequency of following symptoms, such as fatigue, urine yellow, waist and leg pain, waist and leg weakness, amnesia etc. , i. e. kidney deficiency was their main syndrome of TCM （68.4%） and main abnormal constitution of TCM （22. 6% ）, liver pathologic examination results showed that some patients （60. 5% ） had different degree of inflammation and fibrosis. Conclusion： Kidney deficiency syndrome is an important pathogenesis of chronic hepatitis B.