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HDAC5在神经系统中的作用研究进展 被引量：1

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摘要 组蛋白乙酰基转移酶（histone acetyltrans‐ferase ，HAT ）和组蛋白去乙酰化酶（histone deacetylase ，HDAC）在调节组蛋白N 端赖氨酸残基乙酰化或去乙酰化过程中发挥关键作用，是调控染色质重塑和真核细胞基因转录的表现遗传修饰（epigenetic modifications）的机制之一。研究表明HDAC5在调控神经功能方面起到了非常重要的作用。本文就近年来 HDAC5在神经系统中的作用研究进展作一综述。
作者 石俊强 柳玉勇
机构地区 济宁医学院学报编辑部 济宁市精神病防治院
出处 《济宁医学院学报》 2014年第6期441-443,共3页 Journal of Jining Medical University
关键词 HDAC5 神经系统 表观遗传修饰
分类号 R363 [医药卫生—病理学]
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参考文献15

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共引文献8

同被引文献17

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济宁医学院学报
2014年 第6期

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