肾复汤对慢性肾炎患者血清氧化低密度脂蛋白的影响

The Influence of Kidney-Recovery Decoction on Serum Oxidized Low Density Lipoprotein of Patients with Chronic Nephritis

目的:观察肾复汤对痰瘀互结型慢性肾炎伴高脂血症患者血清氧化低密度脂蛋白的影响。方法:选择痰瘀互结型慢性肾炎伴高脂血症患者60例,随机分为治疗组和对照组各30例。对照组给予西药对症治疗,治疗组在对照组的治疗基础上给予肾复汤治疗。结果:治疗后治疗组氧化低密度脂蛋白水平、中医证候积分改善情况均优于对照组(P均<0.01);治疗后治疗组24小时尿蛋白定量优于对照组(P<0.01);与同组治疗前比较,治疗组TG、TC水平有显著性降低(P<0.01)。结论:肾复汤具有降低痰瘀互结型慢性肾炎伴高脂血症患者血清氧化低密度脂蛋白、尿蛋白定量、血脂水平的作用,血清氧化低密度脂蛋白与蛋白尿水平有高度正相关性。

Objective：Tn observe the influence of Kidney - Recovery Decoction on patients with chronic nephritis due to phlegm and blood stasis syndrome,combined with hyperlipidemia. Methods：60 patients with chronic nephritis due to phlegm and blond stasis syndrome,combined with hyperlipidemia,were randomly divided into tile treatment group and the control group, with 30 cases in each group. The patients in the control group were given symptomatic western medicine treatment, while the ones in the treatment group were added Kidney - Recovery＋ Decoction on the basis t^atment of the control group. Results ： In terms of oxidized low density lipopmtein level and TCM syndrome integral improvement, after the treatment, the treatment group was better than those of the control group（ both P 〈 0.01 ） ;In terms of 24h urine protein fixed quantity,the treatment group was better than that of the control group（ both P〈 0.01 ） ;In terms of TG and TC, they were greatly reduced after the treatment within the same treatment group（ P 〈 0.01 ）. Conclusion ： Kidney - Recovery Decoction can reduce serum oxidized low density lipoprotein, urine protein fixed quantity and blood fat level of patients with chronic nephritis due to phlegm and blood stasis syndrome. There is a highly positive correlation between serum oxidized low density lipoprotein and urine protein level.