ghrelin与胰腺疾病的相关性研究进展
摘要
ghrelin是一种新发现的脑肠肽,广泛分布于全身多个系统,具有多种生物学功能。研究表明ghrelin在胰腺内、外分泌性疾病中均有异常表达,可能参与了胰腺疾病的发生发展。此文就ghrelin在胰腺疾病中的研究进展作一综述。
出处
《国际消化病杂志》
CAS
2014年第6期380-382,共3页
International Journal of Digestive Diseases
基金
国家自然科学基金(81060043)
参考文献26
-
1Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth?hormone-releasing acylated peptide from stomach. Nature, 1999, 402: 656-660.
-
2Hosoda H, Kojima M, Matsuo H, et al. Ghrelin and des-acyl ghrelin , two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem Biophys Res Cornmun , 2000, 279: 909-913.
-
3Tolle V, Zizzari p, Tomasetto C, et al. In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat. Neuroendocrinology, 2001, 73: 54-61.
-
4Peino R, Baldelli R, Rodriguez-Garcia J, et al. Ghrelin-induced growth hormone secretion in humans. Eur J Endocrinol, 2000, 143: Rll-RI4.
-
5Mori K, Yoshimoto A, Takaya K, et al. Kidney produces a novel acylated peptide, ghrelin. FEBS Lett, 2000, 486: 213-216.
-
6Korbonits M, Bustin SA, Kojima M, et al. The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors. J Clin Endocrinol Metab, 2001, 86: 881-887.
-
7Tong J, Prigeon RL, Davis HW, et al. Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans. Diabetes, 2010, 59: 2145-2151.
-
8Tong J, Davis HW, Summer S, et al. Acute administration of unacylated ghrelin has no effect on basal or stimulated insulin secretion in healthy humans. Diabetes, 2014, 63: 2309-2319.
-
9Dezaki K, Sone H, Yada T. Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis. Pharmacol Ther , 2008, 118: 239-249.
-
10Dezaki K, Hosoda H, Kakei M, et al. Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2 + signaling in beta-cells: implication in the glycemic control in rodents. Diabetes, 2004, 53: 3142-3151.
-
1谢文超,李平.尿酸与冠心病的相关性研究进展[J].右江民族医学院学报,2014,36(1):85-86. 被引量：4
-
2廖浩,罗健梅,潘婕.营养支持与创伤修复的相关性研究进展[J].护理研究（上旬版）,2006,20(10):2543-2545. 被引量：8
-
3赵贵起,李秀军.近年献血不良反应相关性研究进展[J].河北医药,2009,31(10):1250-1251. 被引量：10
-
4梁敏余,陈沁.国内外病人自我感受负担相关性研究进展[J].全科护理,2014,12(29):2697-2699. 被引量：8
-
5韦晓霜.尿沉渣与尿常规在尿液检验中的相关性研究进展[J].医药前沿,2015,0(2):5-6. 被引量：6
-
6阚佳多.青光眼患者生活质量与社会支持的相关性研究进展[J].健康之路,2016,0(1):21-21. 被引量：1
-
7吴松花,李春玉.脑卒中患者中医体质与生命质量相关性研究进展[J].吉林医学,2014,35(31):7041-7042. 被引量：7
-
8温慧丽,杨敬英,刘志跃,徐霞.颈动脉粥样硬化的超声评价与脑梗死相关性研究进展[J].内蒙古医学杂志,2009,41(S6):38-40.
-
9宋红卫.呼吸机相关性肺炎的预防与护理[J].临床医药文献电子杂志,2015,2(27):5695-5695. 被引量：1
-
10胡美华,杨土保.患者满意度与护理质量持续改进的相关性研究进展[J].医学美学美容（中旬刊）,2014,23(9):280-281.
