体外受精-胚胎移植患者男女双方的生活质量及影响因素分析

Analysis on the quality of life and influencing factors of both male and female patients receiving IVF- ET

目的：探讨体外受精-胚胎移植（IVF-ET）患者男女双方生活质量及影响因素,并分析其间是否存在差异。方法：选取2013年10月~2014年4月在某生殖医院接受IVF-ET的患者351名,采用自制一般情况调查表和中文版SF-36量表对患者进行测评,并用SPSS 17.0进行统计学处理。结果：女性SF-36量表各维度得分均低于男性,其中在生理职能（RP）、躯体疼痛（BP）、一般健康状况（GH）、精力（VT）、社会功能（SF）、情感职能（RE）、精神健康（MH）等方面两组差异有统计学意义（P〈0.05）。年龄、文化程度、收入、不孕年限、手术次数、居住地、妊娠史、流产史对患者生活质量均有影响。多元逐步回归分析显示,男性患者生活质量的主要影响因素为居住地;女性患者生活质量的主要影响因素为接受手术次数及流产史。结论：IVF-ET女性患者生活质量较男性差,双方生活质量的主要影响因素不同。因此,在治疗过程中,应针对男女双方不同的影响因素进行干预,尤其要加倍关注女性患者,着实改善患者生活质量,提高疗效。

Objective： To explore the quality of life and influencing factors of both male and female patients receiving IVF - ET, analyze the difference. Methods： A total of 351 patients receiving IVF - ET in a reproductive hospital from October 2013 to April 2014 were selected, a self-designed questionnaire and SF -36 （Chinese version） were used to evaluate the patients, then the data were analyzed sta- tistically on SPSS 17.0 software. Results： The scores of SF -36 in women were lower than those in men, and there were statistically signifi- cant differences in the scores of role physical （RP）, body pain （BP）, general health （GH）, vitality （VT）, social function （SF）, role emotional （RE） and mental health （MH） between the two groups （P 〈 0. 05） . The influencing factors of quality of life of these patients included age, educational level, income, duration of infertility, operation times, place of residence, pregnancy history and abortion history. Multivariate stepwise regression analysis showed that the main influencing factor of quality of life of male patients was place of residence, while for female patients, the main influencing factors were operation times and abortion history. Conclusion： The quality of life of female patients is poorer than that of male patients, and the main influencing factors of them are different. Thus, intervention measures should be carried out according to different influencing factors in the course of treatment, the female patients should be paid more attention to especially to improve the life quality of patients and curative effect.