舟山海岛地区1523例育龄妇女婚前孕前检测TORCH结果分析及临床意义

Analysis and clinical significance of TORCH results in 1523 cases of fertile women's pre-pregnancy check in premarital examinations in Zhoushan island area

目的分析舟山海岛地区育龄妇女婚前、孕前弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒即TORCH的检测结果,探讨其临床意义。方法采用ELISA法检测普陀区2009年7月-2013年6月进行婚检的育龄妇女血清中TORCH各项特异性Ig M和Ig G抗体。婚检若是Ig M阳性,建议其近期不要怀孕,若R-Ig G阴性的妇女则提供免费疫苗接种。结果 1 523例婚检妇女中,检测出Ig M阳性的妇女,经合理指导,避开高风险期,在孕期呈显著降低或已经愈合检测不到。对R-Ig G阴性的妇女给予风疹疫苗接种后都具有了Ig G抗体,有效降低了风疹病毒感染。结论舟山海岛地区TORCH-Ig M阳性率较低,在孕前接受TORCH检测,排除病原体感染,可有效提高优生率。

Objective This paper analyzes the results of pre- pregnancy TORCH tests of pre- marital fertile women in Zhoushan island area in attempt to explore the clinical significance. Methods The research methodology applies ELISA to check the specificity Ig M and antibody Ig G in fertile women’s blood serum in premarital examination in Putuo district during July of 2009 and June of 2013. If the results show positive Ig M,the examinee will be suggested not to be pregnant shortly. If the results show negative R- Ig G,free vaccination will be given. Results After studying 1 523 cases of premarital examination of fertile women,the risks of positive Ig M in examinees have been reduced greatly or even vanished after reasonable guidance. Those examinees who were found to contain negative Ig G have showed Ig G antibody after being given vaccination and thus risks of being affected by rubella virus have been reduced effectively. Conclusion The research results show that the percentage of positive TORCH- Ig M is quite low in Zhoushan island area and TORCH test in pre- pregnancy check can help avoid the affection of pathogen and improve eugenics rate.