摘要
目的应用中文版FACT-L4.0和WHO DASⅡ(他评版)两种国际生存质量量表作为测定工具,评价榄香稀注射液对治疗非小细胞肺癌患者生存质量的影响,同时以传统的临床疗效评价指标作为参照。方法将200例非小细胞肺癌患者分为观察组及对照组各100例,两组均给予吉西他滨单药化疗:吉西他滨(健泽)1000 mg/m2,静脉滴注30分钟,第1、8、15天,28天为1个周期,连用4个周期。观察组使用榄香稀注射液从化疗的第1天开始用生理盐水500 ml+榄香稀注射液50 ml静脉滴注,1天1次,连用15天,使用4个周期后评价疗效。结果经过4个周期治疗后,观察组患者在生理功能、情绪功能、角色功能、社会活动参与功能及总体健康情况等多个领域评分高于单纯化疗组,两组比较差异有统计学意义(P<0.05),两组患者治疗近期疗效比较差异无显著性(P>0.05)。结论榄香稀注射液可改善非小细胞肺癌患者机体状态,提高患者生存质量。
Objective To evaluate the effect of elemi dilute injection on quality of life of patients with non-small cell lung cancer by two different methods,FACT-DAS Ⅱ L4.0 and WHO.Methods 200 cases of non-small cell lung cancer patients were randomly divided into the observation group and the control group,1 00 cases in each group.All patients were given gemcitabine single-agent chemotherapy,and the observation group was additionally given elemi dilute injection.The total treatment lasted 4 cycles,28 days per cycle.Results The scores of physio-logical function,emotional function,social activities involved function and general healthy condition were obviously higher in the observation group than in the control group （P〈0.05 ）.There was no significance in short-term cura-tive effect between the two groups （P〉0.05 ）.Conclusion Elemi dilute injection can improve the body status and quality of life in the treatment of patients with non-small cell lung cancer.
出处
《临床肺科杂志》
2015年第2期230-233,共4页
Journal of Clinical Pulmonary Medicine
