呼吸科院内尿路感染患者病原菌及耐药分析

Distribution and resistance of pathogenic bacteria in patients with nosocomial urinary tract infections

目的分析呼吸科院内尿路感染患者的病原菌种类分布及其耐药性,为合理用药提供参考。方法回顾性分析呼吸科明确诊断的院内尿路感染患者35例,分析其尿培养病原菌结果。结果 35例患者共分离出58株病原菌,其中革兰阴性菌27株,占46.55%,革兰阳性菌10株,占17.24%,真菌21株,占36.21%。病原菌按检测率排序前3位依次是大肠埃希菌(18.97%)、白色念珠菌(17.24%)、肺炎克雷伯杆菌(10.34%),药物敏感试验显示:革兰阴性菌及革兰阳性菌耐药性严重。结论呼吸科院内尿路感染病原菌以革兰阴性菌为主,且呈多重耐药现象。真菌感染检出率明显增高,临床需加以重视。

Objective To analyze the distribution and drug resistance of the pathogenic bacteria in patients with nosocomial urinary tract infections.Methods The results of urine culture in 35 patients with nosocomial urinary tract infection were analyzed.Results There were 58 strains of pathogenic bacteria isolated,including 27 strains of Gram-negative bacteria （46.55%）,1 0 strains of Gram-positive bacteria （1 7.24%）,and 21 strains of fungi （36.21%）.The top three pathogens were escherichia coli （1 8.97%）,Candida albicans （1 7.24%）and Klebsiella pneumoniae （1 0.34%）.Drug sensitivity test showed that high drug resistance occurred in both Gram-negative bacte-ria and Gram-positive bacteria.Conclusion Nosocomial urinary tract infection in respiratory department is mainly caused by Gram-negative bacteria,showing multi-drug resistance.Fungal infection shows a higher detection rate, which should be paid more attention in clinic.