山东省2006—2012年恙虫病疾病负担分析

Disease burden of scrub typhus in Shandong province,2006-2012

目的研究山东省2006-2012年恙虫病疾病负担，为制订恙虫病的有效防制措施及合理分配有限的卫生资源提供科学依据。方法收集山东省疾病预防控制中心传染病网络报告系统中2006年1月1日-2012年12月31日恙虫病发病数据，采用发病率、伤残调整生命年（DALYs）和DALY强度评价恙虫病的疾病负担。结果2006-2012年山东省全省恙虫病年均发病率为0．35／10万，年均DALYs为63．82人年，年均DALY强度为0．0666人年／10万；城市地区恙虫病年均DALY强度为0．0141人年／10万，低于农村地区的0．1213人年／10万；女性恙虫病年均DALY强度为0．0714人年／10万，高于男性的0．0619人年／10万；各年龄组中，60～69岁年龄组恙虫病年均DALY强度最大，为0．1827人年／10万。结论山东省农村地区恙虫病疾病负担高于城市地区，女性和60～69岁年龄组人群是恙虫病发病的高危人群。

Objective To study the disease burden of scrub typhus in Shandong province from 2006 to 2012, and to provide a scientific basis for developing effective prevention measures and reasonably allocating the limited health re- sources. Methods The indexes of incidence, disability-adjusted life years （DALYs） and DALY rate（ DALY per 100 000 population） recommended by World Health Organization （WHO） were adopted to measure the disease burden of scrub typhus. DALYs and DALY rate were calculated using DisMod I1 and DALY calculation template released by WHO and the overall DALY rate of the province and the rates among rural areas and populations of different gender and age were compared. Results The average annual incidence, DALYs and DALY rate of scrub typhus were 0. 35/105, 63.82years, and 0. 0666 years per 100 000 persons, respectively. The annual incidence and DALY rate in the rural area were higher than thaose of the whole province. The average annual DALY rate was higher in the females than in the males, and it was the highest in the people aged from 60 to 69 years. Conelusion The results demonstrate that the disease burden of scrub typhus increases in Shandong province and the populations of the females aged from 60 to 69 years and living in rural areas are at a higher-risk of the disease.