高效液相色谱法测定滴眼液中盐酸萘甲唑啉和马来酸苯吡丙胺的含量被引量：1

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摘要复方盐酸萘甲唑啉滴眼液是治疗红眼病的新型滴眼液,含盐酸萘甲唑啉(naphazoline chloride,NAP),马来酸苯吡丙胺(pheniramine maleate,PHM)等组分及苯扎氯胺(benzalkonium chloride,BKC)等多种辅料,由于组分较多,难以用一般化学方法直接测定,文献中多采用高效液相色谱法和紫外分光光度法进行测定,本文采用反相高效液相色谱法,以梯度洗脱分离,同时测定其中NAP及PHM的含量,方法简便,结果满意。

作者王玉

机构地区江苏省医药工业研究所

出处《药物分析杂志》 CAS CSCD 北大核心 2002年第4期319-321,共3页 Chinese Journal of Pharmaceutical Analysis

关键词高效液相色谱法马来酸苯吡丙胺复方盐酸萘甲唑啉滴眼液盐酸萘甲唑啉含量测定

分类号 R927.2 [医药卫生—药学] R988.1 [医药卫生—药品]

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参考文献6

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