摘要
[目的]探讨宫颈液基细胞学结果和高危型人乳头瘤病毒（HPV）的相关性,为不同卫生资源地区宫颈癌初筛方法的选择提供科学数据。[方法]2012~2013年选取内蒙古地区20~69岁女性25 731名,采用新柏氏液基细胞学技术开展筛查。并采用Cervista方法进行HPV检测。对细胞学异常或HPV阳性者召回行阴道镜检查。[结果]液基细胞学异常率为5.8%,HPV总阳性率为24.5%,A9型为最常见的HPV感染型别,感染率为7.8%。HPV阳性率和A9型阳性率均与细胞学病变级别显著性正相关,相关系数分别为0.253和0.226（P〈0.001）。[结论]Cervista HPV检测技术是宫颈癌筛查的有效手段,通过该技术对宫颈癌进行初筛并对高危人群分流管理,可扩大筛查覆盖面,使更多百姓受益。
[Purposel To investigate the correlation of the results of liquid-based cytology and high- risk human papillomavirus （HPV） infection,and to provide scientific data for selecting primary screening technologies for eervical cancer in various economic areas. [Methodsl From 2012 to 2013,a total of 25731 women aged 20-69 in Inner Mongolia were screened by Thinprep liquid- based cytology for cervical cancer. The samples were tested for HPV infection by Cervista method. Those women with abnormal cytological results or HPV infection were referred to eolposeopy.[Re- suits] The positivity of cytology and HPV infection was 5.8% and 24.5%,respectively. A9 group were the most common infective HPV types with a positive rate of 7.8%. Both the total HPV infec- tion rate and A9 group HPV infection rate were positively associated with the grade of cytological abnormity,with a correlation coefficient of 0.253 and 0.226,respectively （P〈0.001）. I Conclusion ] Cervista HPV detection is an effective method for primary screening cervical cancer and for the management of high-risk population,amt it can be used in different areas to expand the coverage of screening.
出处
《中国肿瘤》
CAS
2015年第1期76-80,共5页
China Cancer
基金
卫生部医药卫生科技发展计划[卫技中201043号]
