乳酸菌阴道胶囊联合宫颈环形电切术治疗宫颈糜烂伴慢性宫颈炎疗效观察

Curative Effect of Lacidophilin Vaginal Capsules Combined with Loop Electrosurgical Excisional Procedure in the Treatment of Cervical Erosion with Chronic Cervicitis

目的:观察乳酸菌阴道胶囊联合宫颈环形电切术(LEEP)治疗宫颈糜烂伴慢性宫颈炎疗效及安全性。方法:72例宫颈糜烂伴慢性宫颈炎患者随机分为观察组和对照组。两组患者均常规行LEEP,应用抗菌药预防感染1周。观察组在此基础上术后加用乳酸菌活菌阴道胶囊,每次1粒,每晚1次,连用14d。观察两组患者阴道流液时间及阴道出血时间,术后8周复诊评定临床疗效及药品不良反应。结果:观察组术后阴道出血量和阴道出血时间明显少于对照组(P<0.05),临床总有效率为94.44%,明显高于对照组(75.00%,P<0.05)。两组患者治疗期间无明显药品不良反应。结论:乳酸菌阴道胶囊联合LEEP术联合治疗宫颈糜烂伴慢性宫颈炎疗效肯定,能明显缩短创面愈合时间,减少阴道出血量和出血时间,安全性好。

Objective：To discuss the curative effect of lacidophilin vaginal capsules combined with loop electrosurgical excisional procedure （ LEEP） in the treatment of cervical erosion with chronic cervicitis. Methods：Totally 72 cases of patients with cervical ero-sion with chronic cervicitis were selected and divided into the observation group and the control group at random. The patients in the two groups were given routine LEEP with the application of antibiotics to prevent infection for 1 week. The patients in the observation group were additionally given lacidophilin vaginal capsules, placed in the vagina after the operation, one capsule per time at every night for 14 days. The vaginal fluid time and vaginal bleeding time in the two groups were observed. The clinical curative effect and adverse drug reactions （ ADRs） after 8 weeks of the operation were studied and evaluated again. Results： The vaginal bleeding amount and bleeding time in the observation group after the operation was less or shorter than that in the control group （P〈0. 05）. According to the further consultation after 8 weeks of the operation, the total clinical efficiency in the observation group was 94. 44%, which was ob-viously higher than that in the control group（75. 00%,P〈0. 05）. There was no obvious ADR appeared in the two groups during the treatment. Conclusion：Lacidophilin vaginal capsules combined with LEEP has reliable curative effect on cervical erosion with chronic cervicitis, which can obviously shorten the wound healing time and decrease the vaginal bleeding amount and time with high security.