慢性阻塞性肺疾病并发支气管扩张49例临床分析

CLINICAL ANALYSIS OF 49 CASES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH BRONCHIECTASIS

目的探讨慢性阻塞性肺疾病(COPD)并发支气管扩张的临床特点,发病规律及治疗情况,以指导临床工作。方法采用回顾性分析,分析新疆生产建设兵团第四师医院呼吸内科2013年4月—2014年4月收治的新发病的49例COPD并发支气管扩张的患者,了解其发病情况,临床特点,肺功能改变等。同时随机选择同期入住我科的COPD患者49例作为对照组,比较其住院周期,炎性指标及肺功能指标等。结果并发支气管扩张是COPD的常见表现,其发生与患者年龄、病程等有相关性,并发支气管扩张后会增加急性发作的几率、感染的机会和治疗的难度,肺功能下降更加突出。结论 COPD并发支气管扩张的发生随年龄及病程的增加而升高,并发支气管扩张后会加重患者的病情,导致肺功能恶化,增加治疗难度。临床应重视此类患者。

Objective To discuss the clinical characteristics of chronic obstructive pulmonary disease（COPD）with bronchiectasis,as well as pathogenesis regularity and the treatment situation,in order to guide clinical work.Methods A retrospective analysis method was adopted,49 cases of the patients with chronic obstructive pulmonary disease with bronchiectasis from new admitted in our department from2013 to 2014 were recruited,and the incidence,clinical characteristics,changes in pulmonary function,etc were recorded.This research also randomly selected 49 patients with chronic obstructive pulmonary disease in the same period in our department as control group to compare the hospitalization period,inflammatory index and pulmonary function index,etc.Results The merger to bronchiectasis was an common manifestation of chronic obstructive pulmonary disease,it occurred relatively with many factors such as the patients’ age and course of the disease.It would increase the risk of the merger bronchiectasis,infection opportunity of acute attacks and the difficulty of treatment,and reduce lung function obversely.Conclusions The occurrence of chronic obstructive pulmonary disease with bronchiectasis occurs with the increase of the level of age and course,the merger of bronchiectasis can aggravate the patients’ illness,lead to deterioration of lung function,increase the treatment difficulty.Clinical treatment should pay more attention to this kind of patients.