基于先天伏寒病因学说治疗冠心病稳定型心绞痛疗效评价研究

Study on Curative Effect Evaluation of Stable Angina Pectoris of Coronary Heart Disease Based on Congenital Latent Cold Etiology

目的观察伏寒方干预冠心病稳定型心绞痛的疗效,对其进行评价。方法入选100例病人随机分为两组,其中对照组给予西药常规治疗;治疗组给予伏寒颗粒颗粒口服。观察2组治疗前后的心绞痛复发率、心绞痛疗效、心电图疗效,硝酸甘油停减率,中医症候疗效。结果治疗组能够有效缓解心绞痛,改善心肌缺血,但与对照组相比无统计学差异;治疗组能够降低心绞痛复发率,增加硝酸甘油停减率,与对照组相比,有统计学差异(P<0.05);明显改善患者手足凉、心烦、善太息等症状,与对照组相比,有明显统计学差异(P<0.01)。结论基于先天伏寒病因学说对降低冠心病心绞痛复发率,提高生存质量的有一定优势,是具有较强临床指导意义的冠心病心绞痛治疗新模式,为冠心病心绞痛二级预防提供依据。

Objective Observation and evaluation the curative effect of latent pathogenic cold prescription intervention for stable angina pectoris of coronary heart disease. Methods The selected 100 patients were randomly divided into two groups, the control group was treated with routine treatment of Western Medicine, The treatment group was given orally Fu Han granule granule. Two groups were observed before and after treatment of angina recurrence rate, angina pectoris, ECG curative effect, decrease rate of nitroglycerin, TCM Syndromes. Results The treatment group can effectively alleviate angina pectoris, reduce myocardialischemia, but without statistical difference compared with control group. The treatment group could reduce the recurrence of angina rate, increase thewithdrawal rate of nitroglycerin, compared with the control group, there were significant differences （P〈0.05）,The treatment group can significantly improve patients with cold hands and feet, upset, shortness of breath and other symptoms, compared with the control group, there was significant difference （P〈0.01）. Conclusion Congenital latent cold etiology theory has certain advantages for reducing the recurrencerate of angina pectoris of coronary heart diseaseand improving the quality of life has certain advantages, which is with strong clinical significance of the treatment of coronary heart disease with angina new mode, providing the basis for the two grade prevention of coronary heart disease.