血清唾液酸测定对新生儿及幼儿期细菌性肺炎临床意义的比较分析

Comparative Analysis of the Expression of Serum Sialic Acid in Neonates and Children Bacterial Pneumonia

为了探讨血清唾液酸（SA）测定在新生儿及幼儿细菌性肺炎的意义,我们测定了72例新生儿及98例幼儿细菌性肺炎患者血清SA水平。结果显示幼儿肺炎组SA水平在1天~3天内增加到（782.1±16.5）,与幼儿非肺炎对照组（591.9±11.5）比较差异具有统计学意义（P〈0.001）。新生儿非肺炎组SA水平保持在（357.8±9.1）,明显低于幼儿对照组（P〈0.001）。而新生儿肺炎组在起病1天~3天内增加到（604.1±15.4）,明显高于新生儿非肺炎组（P〈0.001）,但与幼儿对照组没有差异。因此,血清SA水平在幼儿时期即已达到成人水平,而新生儿细菌性肺炎患者虽然SA在正常成人标准范围内,但明显高于非肺炎新生儿水平。

To investigate the significance of the detection of sialic acid（SA）in neonates and toddlers bacterial pneumonia,the serum SA levels in 72 cases of neonatal and 98 cases of children patients with bacterial pneumonia were detected.The serum SA levels were increased to 782.1±16.5in children patients within 1~3days.It had significantly difference with the control group.The serum SA levels of non-pneumonia neonates remained in the 357.8±9.1,which is much lower than the non-pneumonia children.The SA levels were 604.1±15.4in neonates＇ patients.However,no difference was found between the non-pneumonia children and the neonates＇ patients.Serum SA level in early childhood had been up to the level of the adult.Although the SA levels of bacterial pneumonia neonates were much lower than the levels of adult,it was really higher than the non-pneumonia children.