七十味珍珠丸对人体肝肾功能和血液系统指标的影响

Study the Effect of Ratnasampil on Human Liver and Kidney Function and Blood System Indicators

目的观察服用含有重金属的七十味珍珠丸对人体肝肾功能和血液系统指标的影响。方法纳入30例病例,服药15 d。采集服药前、服药期间(服药15 d时)和停药后(停药15天时)的血样。检测血常规、肝肾功能和凝血四项,分析七十味珍珠丸对各项指标的影响。结果服药中血小板比服药前增加6.74%,有显著性差异(P<0.05);与服药前相比,停药后嗜碱性粒细胞增加35.90%,有极显著性差异(P<0.01),血肌酐增加7.91%,有显著性差异(P<0.05);但所有差异性变化均在人体指标的正常范围内;其他检测指标服药前、中、后均没有显著性差异(P>0.05)。结论通过七十味珍珠丸对人体肝肾功能和血液系统指标影响的研究,初步判断按藏医理论服用七十味珍珠丸对人体是安全的。

Objective To study the effect of Ratnasampil that contains heavy metals on human liver and kidney function and blood system indicators. Methods Gather 30 cases, take medicine 15 days. Collect blood samples before taking medicine, during the period of taking medicine （ in fifteenth days） and after taking medicine （ in thirtieth days）. Detect complete blood count, liver and kidney function and four items of blood coagulation, analysis the effect of Ratnasampil on the indicators. Results Platelets in- creased by 6.74% during the period of taking medicine than before taking medicine, there has significant differences （ P 〈 0. 05 ） ; Compared with before taking medicine, after taking medicine, Basophils increased by 35.90% , it has significant differences （P 〈 0.01 ）, serum creatinine increased by 7.91%, it has significant differences （P 〈 0.05 ） ; All difference changes were within the normal range of human indicators. Other indicators＇changes have no significant difference （P 〉0.05 ）. Conclusion By stud- ying the effect of Ratnasampil on human liver and kidney function and blood system indicators preliminary judging that according to the theory of Tibetan medicine indicated that the safety of the Ratnasampil to human.