卵巢交界性黏液性肿瘤伴恶变及附壁肉瘤结节1例及文献复习

Ovarian mucinous borderline tumor with malignant change and sarcoma mural nodule:a case report and literature review

目的:探讨1例卵巢交界性黏液性肿瘤伴恶变及附壁肉瘤结节的临床病理特征。方法:对1例诊断为卵巢交界性黏液性肿瘤伴恶变及附壁肉结节患者的临床资料、组织学形态及免疫组化结果进行分析,并对相关文献进行复习。结果:本例为卵巢交界性黏液性肿瘤伴恶变及附壁结节,附壁结节为纤维肉瘤,主要由中等密度的梭形和卵圆形的异型细胞组成,可见较多病理核分裂,梭形和卵圆形的异型细胞Vim(+)。结论:卵巢黏液性肿瘤中附壁肉瘤结节为罕见的伴发病变,临床多以盆腔巨大包块就诊,且附壁肉瘤结节的病理学形态广泛而复杂,极易漏诊、误诊。本文献对1例诊断为卵巢交界性黏液性肿瘤伴恶变及附壁肉瘤结节患者的临床资料、组织学形态及免疫组化结果进行分析,并对相关文献进行复习。对累积资料,避免临床误诊、漏诊具有重要的价值。

Objective： To discuss the clinicopathologic features of ovarian mucinous borderline tumor with malignant change and sarcoma mural nodule. Methods： The clinical data, pathological diagnosis and immunohistochemical results of this case were analyzed,and the related literature was reviewed. Results： This sample was an ovarian mucinous borderline tumor with malignant change and sarcoma mural nodule.Mural nodule was fibrosarcoma, which mainly consisted of medium-density spindle and oval shaped cells. Many pathologic mitosis could be seen, spindle and oval shaped cells were pocitive for Vim（＋）. Conclusion： Ovarian mucinous borderline tumor with malignant change and sarcoma mural nodule is rare, It＇s clinical presentation is usually with a huge pelvic mass. Careful gross examination, extensive sampling and immunohistochemical results are crucial for the correct diagnosis.